Integrating Cryo-OrbiSIMS with Computational Modelling and Metadynamics Simulations Enhances RNA Structure Prediction at Atomic Resolution: Source cryo-OrbiSIMS Data

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Publication date
2023-12-12
Creators
Borkar, Aditi
Kotowska, Anna
Watts, Julie
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Description
This dataset contains the raw cryo-OrbiSIMS peak lists exported from SurfaceLab 7 for the Cas9:sg, ribosome and 7SK RNP complexes. The data is for negative polarity and has been collected in triplicates. The MATLAB codes used for analysing this data, along with gold reference is also included.
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DOI
Subjects
  • Computational biology
  • Models, Molecular
  • RNA -- Computer simulation
  • Mass spectrometry
  • OrbiSIMS, cryo, RNA, mass spectrometry, structure modelling, restraints, metadynamics
  • Biological Sciences::Molecular biology, biophysics & biochemistry
  • Q Science::QP Physiology
Divisions
  • University of Nottingham, UK Campus::Faculty of Science::School of Pharmacy
  • University of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Veterinary Medicine & Science
Deposit date
2023-12-12
Data type
ASCII Text Files
Contributors
  • Ward, Shannon
  • Staley, Ceri
Funders
  • Medical Research Council
  • Anne McLaren Fellowship
  • Alan Webster Endowment
Collection dates
  • Between June 2020 to June 2023
Data collection method
Data collected on the Hybrid SIMS instrument funded by EPSRC at University of Nottingham.
Resource languages
  • en
Publisher
University of Nottingham
CC-BY
Except where otherwise noted, this item's license is described as Creative Commons by Attribution