Show simple item record

Elucidating the molecular landscape of the stratum corneum

dc.contributor.authorStarr, Nichola J
dc.contributor.authorKhan, Mohammed H
dc.contributor.authorEdney, Max
dc.contributor.authorTrindade, Gustavo F.
dc.contributor.authorKern, Stefanie
dc.contributor.authorPirkl, Alexander
dc.contributor.authorKleine-Boymann, Matthias
dc.contributor.authorElms, Chris
dc.contributor.authorO'Mahony, M.
dc.contributor.authorBell, Mike
dc.contributor.authorAlexander, Morgan R.
dc.contributor.authorScurr, David
dc.contributor.otherStarr, Dr Nichola
dc.contributor.otherKhan, Mohammed H
dc.contributor.otherEdney, Max
dc.date.accessioned2022-03-18T08:05:28Z
dc.date.available2022-03-18T08:05:28Z
dc.date.issued2022-03-18
dc.identifier.urihttps://rdmc.nottingham.ac.uk/handle/internal/9488
dc.description.abstract• Characterization of the molecular structure of skin, especially the barrier layer, the stratum corneum using 3D OrbiSIMS. • Understand the chemical variations relating to fundamental biological processes, such as the epidermal cholesterol sulfate. • Investigate the non-homogeneity of the stratum corneum, both laterally and as a function of depth. Including the distribution and localisation of key components in the skin e.g. fatty acids, ceramides and natural moisturising factors. • Demonstrate the permeation of a commercially important anti-aging peptide into human stratum corneum.en_UK
dc.language.isoenen_UK
dc.publisherThe University of Nottinghamen_UK
dc.rightsCC-BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.lcshSkinen_UK
dc.subject.lcshEpidermisen_UK
dc.subject.lcshEpidermis -- Imagingen_UK
dc.subject.lcshSecondary ion mass spectrometryen_UK
dc.subject.meshSkin Physiological Phenomenaen_UK
dc.subject.meshEpidermisen_UK
dc.subject.meshSpectrometry, Mass, Secondary Ionen_UK
dc.titleElucidating the molecular landscape of the stratum corneumen_UK
dc.identifier.doihttp://doi.org/10.17639/nott.7170
dc.subject.freeSkin, Stratum Corneum, 3D OrbiSIMS, Mass Spectrometry, SIMSen_UK
dc.subject.jacsSubjects Allied to Medicine::Anatomy, physiology & pathology::Physiologyen_UK
dc.subject.lcQ Science::QP Physiologyen_UK
dc.contributor.corporateWalgreens Boots Allianceen_UK
uon.divisionUniversity of Nottingham, UK Campus::Faculty of Science::School of Pharmacyen_UK
uon.funder.controlledOtheren_UK
uon.datatype3D mass spectrometry files (itm), Graphs, Imagesen_UK
uon.funder.freeInnovateen_UK
uon.funder.freeICASEen_UK
uon.funder.freeCDTen_UK
uon.funder.freeICASE Instrument Granten_UK
uon.collectionmethod3D OrbiISIMS, ION ToF, Excel, GraphPad, Mathlaben_UK
uon.preservation.rarelyaccessedtrue


Files in this item

Thumbnail
Name:
PNAS Raw Data.zip
Size:
618.8Mb
Format:
Unknown
View/Open
Thumbnail
Name:
PNAS Raw Data.zip
Size:
618.8Mb
Format:
Unknown
View/Open

This item appears in the following Collection(s)

  • Public Research Data
    A collection of research data, held in this repository, that is publicly available, except where individual embargoes apply

Show simple item record

CC-BY
Except where otherwise noted, this item's license is described as Creative Commons by Attribution