Browsing University of Nottingham Research Data Management Service by Subject "Lipids"
Now showing items 1-6 of 6
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Age-related changes to human stratum corneum lipids detected using ToF-SIMS following in vivo sampling
(University of Nottingham, 2016-04-30)This work demonstrates the ability to detect changes in both quantity and spatial distribution of human stratum corneum (SC) lipids from samples collected in vivo. The SC functions as the predominant barrier to the body, ... -
Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis
(The University of Nottingham, 2016-07-01)Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) ... -
Mass-spectral data generated by lipidomics analysis of samples from dairy cattle
(The University of Nottingham, 2025-01-28)Samples were collected from dairy cows to investigate how the lipid fingerprint alters with lameness. Samples were analysed using untargeted LC-MS -
Molecular formula prediction for chemical filtering of 3D OrbiSIMS Datasets
(The University of Nottingham, 2022-02-08)3D OrbiSIMS raw data required to reproduce figures in the manuscript linked to this repository. File formats are itm., enabling access to both spectral and depth profiling data for each series. -
Molecular orientation and stratification revealed in RNA-lipid nanoparticles using Cryogenic Orbitrap Secondary Ion Mass Spectrometry (Cryo-OrbiSIMS)
(Springer Nature, 2025-01-14)Lipid nanoparticle-RNA formulations are used for the delivery of vaccines and other therapies. RNA molecules are encapsulated within their interior through electrostatic interactions with positively charged lipids. The ... -
Spatially Resolved Molecular Analysis of Host Response to Medical Device Implantation Using the 3D OrbiSIMS Highlights a Critical Role for Lipids
(University of Nottingham, 2024-02-13)The data here was used to produce the figures in the submission:- Advanced Science Feb 2024 W. Suvannapruk, L. E Fisher, J. C Luckett, M. K Edney, A. M Kotowska, D.-H. Kim, D. J Scurr, A. M Ghaemmaghami, M. R Alexander* ...