Raw data for new compounds described in the paper: "Enantioselective synthesis of chiral cyclopent-2-enones by nickel-catalyzed desymmetrization of malonate esters"
dc.contributor.author | Lam, Hon Wai | |
dc.contributor.other | Karad, Somnath | |
dc.contributor.other | Panchal, Heena | |
dc.contributor.other | Clarke, Christopher | |
dc.contributor.other | Lewis, William | |
dc.date.accessioned | 2018-05-22T15:15:54Z | |
dc.date.available | 2018-05-22T15:15:54Z | |
dc.date.issued | 2018-05-22 | |
dc.identifier.uri | https://rdmc.nottingham.ac.uk/handle/internal/360 | |
dc.description.abstract | Raw data for new compounds described in the paper: "Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters". The enantioselective synthesis of highly functionalized chiral cyclopent-2-enones by the reaction of alkynyl malonate esters with arylboronic acids is described. These desymmetrizing arylative cyclizations are catalyzed by a chiral phosphinooxazoline–nickel complex, and cyclization is enabled by the reversible E/Z isomerization of alkenylnickel species. The general methodology is also applicable to the synthesis of 1,6-dihydropyridin-3(2H)-ones. | en_UK |
dc.language.iso | en | en_UK |
dc.publisher | The University of Nottingham | en_UK |
dc.subject.lcsh | Chemicals -- Properties | en_UK |
dc.subject.lcsh | Enantioselective catalysis | en_UK |
dc.subject.lcsh | Asymmetric synthesis | en_UK |
dc.subject.lcsh | Chemical processes | en_UK |
dc.title | Raw data for new compounds described in the paper: "Enantioselective synthesis of chiral cyclopent-2-enones by nickel-catalyzed desymmetrization of malonate esters" | en_UK |
dc.identifier.doi | http://doi.org/10.17639/nott.356 | |
dc.subject.free | Raw data for new compounds described in the paper: "Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters " | en_UK |
dc.subject.jacs | Physical sciences::Chemistry::Physical chemistry | en_UK |
dc.subject.jacs | Physical sciences::Chemistry::Organic chemistry | en_UK |
dc.subject.lc | Q Science::QD Chemistry::QD450 Physical and theoretical chemistry | en_UK |
dc.subject.lc | Q Science::QD Chemistry::QD241 Organic chemistry | en_UK |
uon.division | University of Nottingham, UK Campus::Faculty of Science::School of Chemistry | en_UK |
uon.funder.controlled | Other | en_UK |
uon.funder.controlled | Engineering & Physical Sciences Research Council | en_UK |
uon.datatype | IR, NMR, mass spectrometry, and HPLC data | en_UK |
uon.funder.free | European Union Horizon 2020 (Marie Sklowdowska-Curie Individual Fellowship) | en_UK |
uon.funder.free | University of Nottingham | en_UK |
uon.funder.free | GlaxoSmithKline | en_UK |
uon.grant | 702386 | en_UK |
uon.grant | EP/M506588/1 | en_UK |
uon.collectionmethod | Using IR, NMR, and mass spectrometers, and HPLC machines | en_UK |
uon.preservation.rarelyaccessed | true | |
dc.relation.doi | 10.1002/anie.201805578 | en_UK |
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