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dc.contributor.authorCeliz, Adam
dc.contributor.authorSmith, James
dc.contributor.authorDenning, Chris
dc.contributor.authorAlexander, Morgan
dc.description.abstractA scalable and cost-effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial media is presented. This substrate can be applied to common cultureware and used off-the-shelf after long-term storage. Expansion and differentiation of hPSCs are performed entirely on the polymeric surface, enabling the clinical potential of hPSC-derived cells to be realized. Data presented herein includes time-of-flight secondary-ion mass spectrometry (ToF-SIMS), X-ray photoelectron spectroscopy (XPS), water contact angle (WCA) measurements, fluorescence microscopy, cell electrophysiology, nuclear magnetic resonance (NMR) spectroscopy, gel permeation chromatography (GPC). Please note that this data set is in two parts, the second part of which can be found here:
dc.publisherUniversity of Nottinghamen_UK
dc.sourceSee methods in manuscript (DOI: 10.1002/adma.201501351)en_UK
dc.subject.lcshPolymers in medicineen_UK
dc.subject.lcshStem cellsen_UK
dc.subject.lcshHuman cell cultureen_UK
dc.subject.lcshCell differentiationen_UK
dc.subject.meshStem Cellsen_UK
dc.subject.meshCell Culture Techniquesen_UK
dc.subject.meshCell Differentiationen_UK
dc.titleDiscovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation - Supporting data 1en_UK
dc.subject.freehigh throughput; human pluripotent stem cells; materials discovery; polymer microarrays; stem cell differentiation; ToF-SIMS; XPS; WCA; Cell Microscopy; Electrophysiology; NMR and GPC datasets.en_UK
dc.subject.jacsJACS Subjects::Medicine and Dentistry::Clinical medicineen_UK
dc.subject.jacsJACS Subjects::Biological Sciences::Molecular biology, biophysics & biochemistryen_UK
dc.subject.jacsJACS Subjects::Biological Sciences::Biology::Cell biologyen_UK
dc.subject.jacsJACS Subjects::Physical sciences::Chemistry::Analytical chemistryen_UK
dc.subject.jacsJACS Subjects::Physical sciences::Chemistry::Organic chemistry::Polymer chemistryen_UK
dc.subject.jacsJACS Subjects::Physical sciences::Materials scienceen_UK
dc.subject.jacsJACS Subjects::Engineering::Chemical, process & energy engineering::Chemical engineering::Biochemical engineeringen_UK
dc.subject.lcLibrary of Congress Subject Areas::T Technology::TP Chemical technology::TP1080 Polymers and polymer manufactureen_UK
dc.subject.lcLibrary of Congress Subject Areas::R Medicine::R Medicine (General)::R855 Medical technology. Biomedical engineering. Electronicsen_UK - 01/06/2015en_UK
uon.divisionFaculties, Schools and Departments::University of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Medicineen_UK
uon.funder.controlledFunders::Engineering & Physical Sciences Research Councilen_UK
uon.funder.controlledFunders::Wellcome Trusten_UK
uon.funder.controlledFunders::Biotechnology & biological Sciences Research Councilen_UK
uon.funder.controlledFunders::Medical Research Councilen_UK
uon.datatypeRaw data files for ToF-SIMS, XPS, WCA, Cell Microscopy, Electrophysiology, NMR and GPC datasets.en_UK
uon.funder.freeUK Regenerative Medicine Platformen_UK
uon.funder.freeBritish Heart Foundationen_UK
uon.funder.freeHeart Research UKen_UK
uon.funder.freeNational Centre for the Replacement, Refinement and Reduction of Animals in Researchen_UK
uon.parentproject'Future-Proof' Synthetic Surfaces for the Automated Manufacture of Human Pluripotent Stem Cells (EP/H045384/1)en_UK
uon.collectionmethodToF-SIMS (SurfaceLab - ION-TOF), XPS (CASA XPS), WCA, Cell Microscopy (IMSTAR), Electrophysiology, NMR (BRUKER) and GPC (Shimadzu) datasets.en_UK
uon.legalA patent has been filed in relation to the work described herein.en_UK
uon.rightscontactUniversity of Nottinghamen_UK
uon.institutes-centresResearch institutes and centres::University of Nottingham, UK Campus::Biomolecular Sciences, Centre foren_UK

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