BRIGhTMIND trial-motivating mechanism of action analysis plan: Magnetic Resonance Spectroscopy
Description
This is the acquired spectra processing and statistical analysis plans for the BRIGhTMIND clinical trial.
It demonstrates hypotheses related with magnetic resonance spectroscopy (MRS) in the BRIGhTMIND and how to test the hypotheses. Detailed information about the BRIGhTMIND can be found in the published protocol paper (Morriss et al., 2020, doi: 10.1136/bmjopen-2020-038430). Imaging acquisition and analysis methods can be found in the magnetic resonance imaging protocol paper (Pszczolkowski et al., 2022, doi: 10.2196/31925).
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Subjects
- Magnetic resonance imaging
- Magnetic brain stimulation
- Depression, Mental
- MRS, BRIGhTMIND, Major Depressive Disorder
- Subjects Allied to Medicine::Anatomy, physiology & pathology::Neuroscience
- R Medicine::RC Internal medicine::RC 321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions
- University of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Medicine
Research institutes and centres
- University of Nottingham, UK Campus::Mental Health, Institute of
Deposit date
2023-02-10Data type
PDF documentContributors
- Cottam, William
- Berrington, Adam
- Parihk, Jehill
- Barbourina-Brooks, Ben
- Briley, Paul
- Webster, Lucy
- Blamire, Andrew
- Liddle, Peter
- Auer, Dorothee
- Morriss, Richard
Funders
- National Institute for Health Research
Grant number
- EME Project:16/44/22 ACF-2019-12-007
Data collection method
Analysis PlanResource languages
- en