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Cocoa flavanol supplementation and the effect on insulin resistance in females who are overweight or obese; a randomized, placebo-controlled trial

dc.contributor.authorMacdonald, Ian A
dc.contributor.authorSimpson, Elizabeth J
dc.contributor.otherMacdonald, Ian A
dc.contributor.otherSimpson, Elizabeth J
dc.contributor.otherDunlop, Mandy V
dc.contributor.otherMendes, Buddhike
dc.contributor.otherKwik Uribe, Catherine
dc.contributor.otherSchroeter, Hagen
dc.coverage.spatialNottinghamshire UKen_UK
dc.date.accessioned2023-01-20T14:08:21Z
dc.date.available2023-01-20T14:08:21Z
dc.date.issued2023-03-01
dc.identifier.urihttps://rdmc.nottingham.ac.uk/handle/internal/10438
dc.description.abstractThere is interest in the impact that dietary interventions can have on preventing the transition from insulin resistance to type 2 diabetes, including a suggestion that bioactive components of cocoa may enhance fasting insulin sensitivity. However, a role for Cocoa Flavanols in reducing insulin resistance in the insulin-stimulated state, an important risk factor for cardiovascular disease, is unresolved. This study investigated whether cocoa flavanol consumption improved whole-body insulin-mediated glucose uptake in females with overweight/obesity, using a randomized, double-blinded, placebo-controlled, parallel-group design.en_UK
dc.language.isoenen_UK
dc.publisherUniversity of Nottinghamen_UK
dc.relation.urihttps://clinicaltrials.gov/ct2/show/NCT01201590en_UK
dc.rightsCC-BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.lcshInsulin resistanceen_UK
dc.subject.lcshFlavonoids -- Physiological effecten_UK
dc.subject.lcshCocoaen_UK
dc.subject.lcshDietary supplements -- Therapeutic useen_UK
dc.subject.meshInsulin Resistanceen_UK
dc.subject.meshFlavonoidsen_UK
dc.subject.meshDiet Therapyen_UK
dc.titleCocoa flavanol supplementation and the effect on insulin resistance in females who are overweight or obese; a randomized, placebo-controlled trialen_UK
dc.identifier.doihttp://doi.org/10.17639/nott.7268
dc.subject.freeInsulin resistance; Cocoa flavanols; Females; Hyperinsulinemic Clamp; HOMA-IR; Quickien_UK
dc.subject.jacsSubjects Allied to Medicineen_UK
dc.subject.lcW Medicine and related subjects (NLM Classification)::WK Endocrine systemen_UK
dc.subject.lcR Medicine::RC Internal medicineen_UK
dc.contributor.corporateMars Incorporateden_UK
dc.date.collectionMarch 2009 - October 2010en_UK
uon.divisionUniversity of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Life Sciencesen_UK
uon.funder.controlledOtheren_UK
uon.datatypeRaw Data; Physiological Measurementsen_UK
uon.funder.freeMars Incorporateden_UK
uon.grantPO:1000165377en_UK
uon.collectionmethodData Collection Protocolen_UK
uon.rightscontactIA Macdonald, University of Nottinghamen_UK
uon.rightscontactEJ Simpson, University of Nottinghamen_UK
uon.preservation.rarelyaccessedtrue
uon.identifier.risprojectRIS 33612en_UK


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