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Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis
(The University of Nottingham, 2016-07-01)
Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) ...
Raw data relating to Biomaterials Science paper - Bioreducible cross-linked core polymer micelles enhance in vitro activity of methotrexate in breast cancer cells
(University of Nottingham, 2017-06-28)
Experimental data used in Gulfam M. et al. Biomater. Sci., 2017, 5, 532–550
NMR, GPC, DLS and key physical science data. Cell culture studies supporting figures in the paper
Enhanced vitamin C skin permeation from supramolecular hydrogels, illustrated using in situ ToF-SIMS 3D chemical profiling
(The University of Nottingham, 2019-03-15)
This research explores the use of ToF-SIMS 3D profiling to provide information on the skin permeation of active compounds, specifically vitamin C delivery from different formulation types.
Biocompatible unimolecular micelles obtained via the Passerini reaction as versatile nanocarriers for potential medical applications
(University of Nottingham, 2018-06-20)
Drug loading and encapsulation efficiency, In vitro drug release study, Cell culture, Viability assay, Bacterial susceptibility assay, Cellular uptake study.
In vitro lipolysis/microsomal metabolism approach for the prediction of oral bioavailability of BCS II drugs in lipidic formulations
(The University of Nottingham, 2016-08-24)
Lipidic formulations (LFs) are increasingly utilized for the delivery of drugs that belong to class II of the Biopharmaceutics Classification System (BCS). The current work proposes, for the first time, the combination ...
Effect of surfactant on Pseudomonas aeruginosa colonization of polymer microparticles and flat films
(The University of Nottingham, 2018-05-09)
Data relating to the paper: "Effect of surfactant on Pseudomonas aeruginosa colonization of polymer microparticles and flat films."
Micro- and nanoparticles are of great interest because of their potential for trafficking ...
Supramolecular Nucleoside-Based Gel: Molecular Dynamics Simulation and Characterization of Its Nanoarchitecture and Self-Assembly Mechanism
(ACS Publications, 2019-02-14)
Among the diversity of existing supramolecular hydrogels, nucleic acid-based hydrogels are of particular interest for potential drug delivery and tissue engineering applications because of their inherent biocompatibility. ...
Vaccine NMA data & syntax
(The University of Nottingham, 2020-01-17)
Psychological and behavioural factors influence the effectiveness of vaccines. This has led to interest in the potential for non-pharmacological treatments, which modify these factors, to enhance vaccine effectiveness. We ...
Fungal biofilm formation on potential anti-attachment materials
(The University of Nottingham, 2020-06-02)
(Meth)acrylate polymers showing the lowest fungal attachment (from a preceding microarray-spot screen) were assayed by scale-up to coat the 6.4-mm diameter wells of 96-well plates. Polymers showing surface cracking were ...
Fasted state gastric antral motility MRI and manometry AUC anonimyzed data sets
(The University of Nottingham, 2020-08-13)
The Excel sheet deposited contains the anonymized individual data (n=421) and the time course data for the fasted state gastric antral motility study, comparing directly concomitant MRI and manometry techniques in healthy ...