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Single cell tracking on polymer microarray reveals the impact of surface chemistry on Pseudomonas aeruginosa twitching speed and biofilm development
(The University of Nottingham, 2020-09-01)
Dataset contains raw and processed data used for the creation of figures in publication entitled 'Single cell tracking on polymer microarray reveals the impact of surface chemistry on Pseudomonas aeruginosa twitching speed ...
Immune-instructive polymers
(The University of Nottingham, 2020-05-01)
We identify polymers which instruct different immunological responses by modulating macrophage attachment and polarisation to pro-inflammatory (M1-like) or anti-inflammatory (M2-like) phenotypes. These immune-instructive ...
Vaccine NMA data & syntax
(The University of Nottingham, 2020-01-17)
Psychological and behavioural factors influence the effectiveness of vaccines. This has led to interest in the potential for non-pharmacological treatments, which modify these factors, to enhance vaccine effectiveness. We ...
Validating a predictive structure–property relationship by discovery of novel polymers which reduce bacterial biofilm formation
(The University of Nottingham, 2020-06-26)
Dataset contains raw and processed data used for the creation of figures in publication entitled 'Validating a Predictive Structure – Property Relationship by Discovery of Novel Polymers which Reduce Bacterial Biofilm Formation'
Fungal biofilm formation on potential anti-attachment materials
(The University of Nottingham, 2020-06-02)
(Meth)acrylate polymers showing the lowest fungal attachment (from a preceding microarray-spot screen) were assayed by scale-up to coat the 6.4-mm diameter wells of 96-well plates. Polymers showing surface cracking were ...
Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation
(The University of Nottingham, 2020-05-05)
Material topography is known to influence macrophage attachment and phenotype, providing opportunities for the rational design of ‘immune-instructive’ topographies to modulate macrophage function and thus foreign body ...
Design and evaluation of new quinazolin-4(3H)-one derived PqsR antagonists as quorum sensing quenchers in Pseudomonas aeruginosa
(The University of Nottingham, 2022-04-22)
A study focused on the design, synthesis and evaluation of pqs quorum sensing inhibitors
Mushroom-shaped structures formed in Acinetobacter baumannii biofilms grown in a roller bioreactor are associated with quorum sensing dependent Csu-pilus assembly
(The University of Nottingham, 2022-05-24)
Study on the influence of quorum sensing regulation on biofilm maturation in Acinetobacter baumannii
Single cell metabolic profiling of macrophages using 3D OrbiSIMS: correlations with phenotype
(The University of Nottingham, 2022-06-10)
ABSTRACT: Macrophages are important immune cells that respond to environmental cues acquiring a range of activation status represented by pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes at each end of their ...
Molecular nanomachines for photoactivated biofilm disruption
(The University of Nottingham, 2024-01-01)
Study on the impact of molecular nanodrills on bacterial viability and biofilm formation