Browsing University of Nottingham Research Data Management Service by Author "Ghaemmaghami, Amir"
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Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation
Alexander, Morgan (The University of Nottingham, 2020-05-05)Material topography is known to influence macrophage attachment and phenotype, providing opportunities for the rational design of ‘immune-instructive’ topographies to modulate macrophage function and thus foreign body ... -
Immune-instructive polymers
Ghaemmaghami, Amir (The University of Nottingham, 2020-05-01)We identify polymers which instruct different immunological responses by modulating macrophage attachment and polarisation to pro-inflammatory (M1-like) or anti-inflammatory (M2-like) phenotypes. These immune-instructive ... -
Microparticles decorated with cell-instructive surface chemistries actively promote wound healing
Ghaemmaghami, Amir; Alexander, Morgan; Irvine, Derek (The University of Nottingham, 2022-12-01)Wound healing is a complex biological process involving close crosstalk between various cell types. Dysregulation in any of these processes, such as in diabetic wounds, results in chronic non-healing wounds. Fibroblasts ... -
Single cell metabolic profiling of macrophages using 3D OrbiSIMS: correlations with phenotype
Suvannapruk, Waraporn; Kim, Dong-Hyun (The University of Nottingham, 2022-06-10)ABSTRACT: Macrophages are important immune cells that respond to environmental cues acquiring a range of activation status represented by pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes at each end of their ...